TBT2020: Translational Biotechnology: A Journey from Laboratory to Clinics |
Website | https://sites.google.com/view/translationalbiotechnology/home |
Submission link | https://easychair.org/conferences/?conf=tbt2020 |
Abstract registration deadline | December 15, 2019 |
Submission deadline | December 31, 2019 |
Call for Book Chapters- Elsevier 2020
Book Title: Translational Biotechnology: A Journey from Laboratory to Clinics
Editor: Dr Yasha Hasija, Associate Professor
Department of Biotechnology, Delhi Technological University
Mail- tbiotechnology@gmail.com
Aims and Scope:
The aim of this book is to bring together a multidisciplinary approach for understanding the nuances of translational research in the field of biotechnology and it will give an insight into the application side. There is a need for clinical scientists who can be effective facilitators of the translational process. However, existing norms award biomedical researchers according to individual achievements and not as a group. Increased complexity in biomedical research has distanced the laboratory from clinical scientists, and thus there is a need for clinical scientists who can serve as facilitators of the translational process. However, the training of such individuals is lengthy and expensive, and incentives are needed. Moreover, training such as facilitator experts is expensive and requires much institutional collaboration. This book aims to elaborate on the importance of translational research with illustrative examples and it addresses the challenges faced. It will discuss practical approaches in the development of personalized medicine, systems and dynamical medicine. It intends to outline future research prospects of the bench to bedside approach. The purpose is to explain biotechnology in a different light than most textbooks i.e., it uses an application-oriented approach.
Scope:
- The science and technology of underlying diseases and their interventions;
- The role of biotechnology in developing new therapies;
- The regulatory framework that will impact the use of new interventions; and
- The private and public capital that will develop the growing biotechnology and biomedical markets.
The integrative and multidisciplinary approaches in the book may be helpful for bridging the gaps between fundamental and functional research. This book intends to provide a state-of-the-art and integrative view of translational biotechnology by covering topics from basic concepts to novel methodologies. This book can be used by biotechnology and biomedical students, scientific experts, and health professionals at all levels. It aspires to promote research in the field of biotechnology that is translational in nature, is cost-effective and readily available to the community for use.
Table of Contents:
This book is divided into three major parts.
- The first part of the book gives a brief introduction and discusses the definition and distinguishes between translational and basic research.
- The second part describes resources, tools, and applications for understanding disease complexity, finding effective biomarkers, production of drugs, creation of better disease models, novel therapies and personalized medicine.
- The third part of the book focuses on translational bioinformatics, synthetic biology and systems approach in drug design and discovery, clinical applications and recent research work in the field.
We welcome book chapter contributions on the following themes. There’s a brief overview on the themes (but not limited to) that are to be covered in the respective themes.
1. Introduction to Translational Biotechnology
- A brief overview of basic research, clinical research and translational research.
- Definition the term “translational” with respect to research in biotechnology and biomedicine, as defined by the European Society of Translational Medicine, explaining the bench-bedside-community approach.
- The importance of biotechnology in translational biomedicine, outlining the importance of integrative research.
This chapter aims to capture the essence of experimental medicine, biotechnological products, bioinformatics tools, etc., in formulating disease intervention strategies.
2. Biotechnology Based Therapeutics
- Advanced biotechnology principles or processes from disease and therapeutic properties.
- Emphasize on technologies that lead to or assist in the discovery of therapy.
- Critical processes in the flow from basic science to practical application in the clinic via clinical trials and translational studies.
- Advancement in devices, biologics, vaccines etc. as an introduction to biotechnology products that are being used in therapy.
- Important pharmacologic principles.
3. Pathway and Target Discovery
- The pathway or target discovery.
- Discovery of new targets and pathways for novel biologics and therapeutic treatments.
- The molecular basis of human diseases with an emphasis on novel therapeutic approaches.
- Discussion of original research articles and latest trends.
4. Biological Therapeutic Modalities
- Small molecules, therapeutic proteins, monoclonal antibodies, engineered multi-specific antibodies, cell-based immunotherapies, stem cell applications, viral therapy and microbiome-based therapeutics. Both classical and new modalities.
- Modalities currently available and the ones that are being developed for the detection and prediction of disease progression and drug responses, for improving the safety, utilization, and effects among new and existing drugs, such as the strategies in drug combinations and drug repositioning.
5. Translational Bioinformatics
- Applications of translational bioinformatics for the development of systems and dynamical medicine with the predictive, preventive, personalized, and participatory (P4) features.
- Bioinformatics methods and resources for “omics” studies and tools for the studies of Disease Phenotype and Drug Responses.
- Studies relating to the use of bioinformatics for translational research such as for cancer risk prediction, cardiovascular diseases, age-related disorders biomarker discovery etc.
6. System Biology and Synthetic Biology
- Identification of systems-based and dynamical biomarkers representing the evolving processes in cancer development may help support cancer precision medicine.
- Concept-based on non-linear dynamical theory and complex network theory explaining the importance of dynamical network biomarkers and their ability to distinguish between a pre-disease state and disease state which was not possible earlier with network biomarkers or molecular biomarkers.
- Studies showing ways of determining DNBs.
7. Drug Discovery, Personalized and Precision Medicine
- Challenges in Drug Discovery and System Based Model for diseases, especially complex disorders.
- Outline in-silico drug designing and recent advances in the field, citing examples of success stories of “from bench to bedside”.
- Artificial intelligence-based technology that is being incorporated in biotechnology for rapid and cost-effective results, and how it can be used for drug discovery.
- Precision medicine and methods for translational research in the making of personalized medication such as biomarker identification.
- Short prelude to cost-effective models of precision medicine.
8. Socio-Economic Impact of Translational Biotechnology
- Socio-economic aspects of translational biotechnology.
- Feasibility of carrying out translational research, its availability to the public.
- The social impact caused by discoveries made in the laboratory.
- Challenges faced and ways to overcome them.
- Elaborate on the technological and monetary challenges faced in developing and under-developed countries in carrying out translational research.
- Legal and ethical aspects of translational biotechnology.
Publication Schedule:
Abstract Submission (abstract with TOC): December 31, 2019
Preliminary acceptance/rejection notification: January 20, 2020
Full chapter submission: March 25, 2020
First review notification: May 01, 2020
Revised paper submission: June 01, 2020
Acceptance/Rejection notification: July 01, 2020
Camera-Ready Submission: July 15, 2020
Submission Procedure:
Submission of chapter(s) via e-mail only:
Prospective authors need to electronically submit their abstract (100-150 words and 5-10 keywords) of your chapter along with tentative TOC using the EasyChair submission system (EasyChair Submission). The abstract must use American spelling as the rest of the manuscript and abbreviations must be avoided unless it is firmly established in the field. Upon acceptance of the proposal, further instructions for submission guidelines according to the Elsevier will be communicated. Authors are invited to submit original, high quality, unpublished work on their chosen topic.
The authors are requested to mention the names of all contributing authors, the chapter title/no for their abstract along with affiliation and respective contact details (email id).
Submitted chapters should be prepared using Latex or Microsoft Word, and according to the Elsevier's chapter templates. Submitted manuscripts will be refereed by at least two independent and expert reviewers for quality, correctness, originality, and relevance. The accepted contributions will be published
Contact for any further queries:
Dr Yasha Hasija- Department of Biotechnology, Delhi Technological University, Bawana Road, Delhi-110042
Email id- tbiotechnology@gmail.com