It is necessary to invest in the professional development of nurses, encouraging them to practice taking care of themselves, not only providing others with more conscious and safe care, but also to provide a satisfactory level of well-being in what they do. your health. Objective: to discuss the main findings about nursing self-care in the light of Symbolic Interactionism. Methods: integrative literature review conducted in the LILACS, BDENF, MEDLINE/PubMed and SCIELO databases, of studies published between 2014 and 2019, in English, Portuguese and Spanish. Results: 12 studies were analyzed that addressed self-care in a conceptual, theoretical and practical way in the different scenarios that make up nursing, revealing the interpersonal relationships established in the construction of fundamental care. With regard to the discussion of studies in the light of Symbolic Interactionism, no article has used this framework in its analyzes. Conclusion: this review brings to discussion how nurses perceive themselves in the perspective of the care scenario and how they perceive this relationship when the object in question is their own needs for self-knowledge, revealing aspects that clearly relate to the concepts of Symbolic Interactionism.